Factor Deficient Plasmas
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Factor II Deficient PlasmaThrombin or factor II has many effects within the coagulation cascade. It is a serine protease that is responsible for the conversion of the soluble protein into insoluble fibrin. Factor IIa is also responsible for the a… |
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Factor V Deficient PlasmaFactor V or proaccelerin/labile factor is a cofactor of the common pathway. Deficiency can lead to heamorrage. Factor V deficient plasma is an immune depleted plasma that has been immunologically stripped of all of its … |
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Factor VII Deficient PlasmaFactor VII or Proconvertin has a pivitol role in the coagulation cascade and is responsible for initiating the coagulation cascade along with tissue factor. Factor VII is an immune depleted that has been stripped of all… |
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Factor X Deficient PlasmaFactor X is also known as Stuart-Prower Factor or thrombokinase. It is the first factor in the common pathway and is responsibile for cleaving prothrombin in two places which yields the the active form thrombin. Factor … |
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Factor VIII Deficient Plasma with vWFFactor VIII or otherwise known as anti-haemophilic factor is a cofactor of factor IXa which in the presence of Ca+2 and phospholipids form a complex that converts Factor X to Factor Xa. Factor VIII deficient plasma is c… |
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Factor VIII Deficient PlasmaFactor VIII or otherwise known as anti-haemophilic factor is a co-factor of factor IXa which in the presence of Ca2 and phospholipids form a complex that converts Factor X to Factor Xa. Factor VIII deficient plasma is a… |
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Factor IX Deficient PlasmaFactor IX or Christmas Factor acts in its active form by hydrolysing a arginine-isoleucine bond in Factor X to form Factor Xa. Factor IXa also requires calcium, phospholpids and Factor VIII as a Co-Factor to be able to d… |
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Factor XI Deficient PlasmaDeficiency of Factor XI causes the rare disease Haemophilia C and is a autosomal recessive disease. There is little spontaneous bleeding, but surgical procedures may cause excessive blood loss. Factor XI deficent plasma… |
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Factor XII Deficient PlasmaFactor XII is also known as Hageman factor. The activated form of Factor XII activates factor XI and Prekallikrein. Factor XII itself can be converted to its active form Factor XIIa by negatively charged surfaces. … |