Product Information
Collagen is a structural protein which is virtually ubiquitous throughout the human body. During primary Haemostasis following blood vessel injury, the adhesion of platelets to exposed collagen at the site of injury plays a key role in the arrest of bleeding from this site. Any interference with the ability of platelets to interact with exposed collagen is therefore a possible cause of an explained bleeding tendency. Some congenital defects of platelet function, as well as some acquired and drug-induced effects can affect the aggregation of platelets stimulated by collagen. Investigation of the ability of patient platelets to aggregate to a controlled preparation of collagen fibrils is an important part of the investigation of suspected disorders of platelet function.
The reagent contains 200µg/ml of type 1 (>95%) collagen fibrils from bovine skin with added buffer and stabilisers
